TY - JOUR T1 - Angina may trump ischaemia in predicting stable coronary artery disease outcomes, but most cardiovascular events occur in patients without angina or asymptomatic ischaemia JF - Evidence Based Medicine JO - Evid Based Med SP - 111 LP - 111 DO - 10.1136/ebmed-2014-110128 VL - 20 IS - 3 AU - Richard Kones AU - Umme Rumana Y1 - 2015/06/01 UR - http://ebm.bmj.com/content/20/3/111.abstract N2 - Commentary on: Steg PG, Greenlaw N, Tendera M, et al., Prospective Observational Longitudinal Registry of Patients With Stable Coronary Artery Disease (CLARIFY) Investigators. Prevalence of anginal symptoms and myocardial ischemia and their effect on clinical outcomes in outpatients with stable coronary artery disease: data from the International Observational CLARIFY Registry. JAMA Intern Med 2014;174:1651–9OpenUrlCrossRefPubMed.The presence of angina portends a poor prognosis. Greater attention has recently been directed to asymptomatic ischaemia, the severity of which plays a role in development of chest pain1 and is a robust and independent predictor of mortality in patients with stable angina.2 Ischaemia during normal activity markedly raises the relative risk of cardiac events and mortality in patients with or without heart disease.3Modern antianginal drugs, secondary prevention, diagnostic/invasive techniques and … ER -