TY - JOUR T1 - Inhaled fluticasone and budesonide increased the risk of serious pneumonia in COPD JF - Evidence Based Medicine JO - Evid Based Med SP - 116 LP - 116 DO - 10.1136/eb-2013-101695 VL - 19 IS - 3 AU - Patrick White Y1 - 2014/06/01 UR - http://ebm.bmj.com/content/19/3/116.abstract N2 - Commentary on: Suissa S, Patenaude V, Lapi F, et al. Inhaled corticosteroids in COPD and the risk of serious pneumonia. Thorax 2013;68:1029–36.OpenUrlAbstract/FREE Full Text High-dose inhaled corticosteroids (ICS) reduce the rate of exacerbations in severe and very severe chronic obstructive pulmonary disease (COPD) when prescribed with inhaled long-acting β-agonists (LABA).1 ,2 Although LABA+ICS use is now universally recommended for severe and very severe COPD, the magnitude of their effect is disputed and they are associated with a higher risk of pneumonia.3 Risk of pneumonia has been associated particularly with fluticasone propionate, and less clearly with budesonide.4 ,5 Equivalence of potency between different … ER -