TY - JOUR T1 - Inhaled corticosteroids for people with chronic obstructive pulmonary disease are associated with an increased risk of fracture JF - Evidence Based Medicine JO - Evid Based Med SP - 90 LP - 91 DO - 10.1136/ebm.2011.100221 VL - 17 IS - 3 AU - Nirupama Putcha AU - M Bradley Drummond Y1 - 2012/06/01 UR - http://ebm.bmj.com/content/17/3/90.abstract N2 - Commentary on: Loke YK, Cavallazzi R, Singh S. Risk of fractures with inhaled corticosteroids in COPD: systematic review and meta-analysis of randomised controlled trials and observational studies. Thorax 2011;66:699–708.OpenUrlAbstract/FREE Full Text Inhaled corticosteroids (ICS) are recommended for the management of moderate to severe chronic obstructive pulmonary disease (COPD).1 2 Previous investigations on the adverse effects of ICS on bone health in individuals with COPD have yielded conflicting results. Some trials3 have found that ICS can worsen bone mineral density (BMD) but not fracture risk, whereas other studies4 5 have found no such effect. Meta-analyses have also yielded contradictory findings.6 7 Understanding the strength and characteristics of this association is important as fractures can have serious … ER -