TY - JOUR T1 - Percutaneous coronary intervention of culprit and non-culprit coronary arteries in acute ST-elevation MI may improve outcomes JF - Evidence Based Medicine JO - Evid Based Med SP - 96 LP - 96 DO - 10.1136/eb-2013-101618 VL - 19 IS - 3 AU - Stuart H Chen AU - Anjan K Chakrabarti Y1 - 2014/06/01 UR - http://ebm.bmj.com/content/19/3/96.abstract N2 - Commentary on: Wald DS, Morris JK, Wald NJ, et al. Randomised trial of preventive angioplasty in myocardial infarction. N Engl J Med 2013;369:1115–23.OpenUrlCrossRefPubMedWeb of Science The paramount goal of the treatment for acute ST-elevation myocardial infarction (STEMI) is the emergent restoration of blood flow through percutaneous coronary intervention (PCI) of the infarct-related or ‘culprit artery’, generally identified as an occluded vessel from a thrombotic lesion. However, multivessel coronary artery disease (CAD) is frequently present in patients with STEMI and portends a worse prognosis. The optimal revascularisation strategy for non-culprit coronary lesions in STEMI is unclear.1 The current American College of Cardiology Foundation/American Heart Association and European Society of Cardiology guidelines advise against PCI of non-infarct vessels in the acute setting unless haemodynamic compromise is present, owing to a lack of evidence for its benefit in … ER -