TY - JOUR T1 - After a negative screening colonoscopy, a microsimulation model shows that currently recommended strategies are equally effective for rescreening JF - Evidence Based Medicine JO - Evid Based Med SP - 199 LP - 200 DO - 10.1136/eb-2012-101176 VL - 18 IS - 5 AU - Thomas F Imperiale Y1 - 2013/10/01 UR - http://ebm.bmj.com/content/18/5/199.abstract N2 - Commentary on: Knudsen AB, Hur C, Gazelle GS, et al. Rescreening of persons with a negative colonoscopy result: results from a microsimulation model. Ann Intern Med 2012; 157: 611– 20.OpenUrlPubMedWeb of Science Several computer-based decision models have demonstrated the effectiveness and cost-effectiveness of colorectal cancer (CRC) screening with any of the recommended tests and strategies.1 These strategies include annual high-sensitivity guaiac-based faecal occult blood testing or faecal immunochemical testing, CT colonography every 5 years and colonoscopy every 10 years.2 For each strategy, the models simulate CRC-related outcomes such as CRC incidence and mortality, life-years, complications and costs, and assume that persons use the same screening test repeatedly. The models further assume a certain starting age (usually, age 50) for screening the population, which is screened for a certain time interval (usually 25–30 years) and then followed until death. On a continuum with the … ER -