TY - JOUR T1 - Elective colectomy for severe ulcerative colitis may reduce mortality more than medical therapy JF - Evidence Based Medicine JO - Evid Based Med SP - 29 LP - 29 DO - 10.1136/ebmed-2015-110311 VL - 21 IS - 1 AU - Harini Naidu AU - Francis A Farraye AU - Ansu Noronha Y1 - 2016/02/01 UR - http://ebm.bmj.com/content/21/1/29.abstract N2 - Commentary on: Bewtra M, Newcomb CW, Wu Q, et al. Mortality associated with medical therapy versus elective colectomy in ulcerative colitis: a cohort study. Ann Intern Med 2015;163:262–70.OpenUrlCrossRefPubMedThe management of patients with moderate to severe ulcerative colitis (UC) is challenging, and the definition of successful treatment is unclear. Clinical practice is moving from symptomatic improvement to mucosal healing as this has shown to result in longer clinical remission, lower rates of hospitalisation and reduced need for surgery.1 Surgical management is reserved for patients refractory to medical therapy or in those that develop colorectal neoplasia. This study aims to assess whether patients with severe UC have improved survival after elective colectomy compared to those being treated with certain immunosuppressive therapies.A retrospective matched cohort study was conducted … ER -