TY - JOUR T1 - Light to moderate alcohol intake may be associated with non-minimal cancer risk JF - Evidence Based Medicine JO - Evid Based Med SP - 77 LP - 77 DO - 10.1136/ebmed-2015-110299 VL - 21 IS - 2 AU - Ziming Xuan Y1 - 2016/04/01 UR - http://ebm.bmj.com/content/21/2/77.abstract N2 - Commentary on: Cao Y, Willett WC, Rimm EB, et al. Light to moderate intake of alcohol, drinking patterns, and risk of cancer: results from two prospective US cohort studies. BMJ 2015;351:h4238.Empirical evidence has linked excessive alcohol consumption to increased risk of various cancers including those of the oral cavity, oesophagus, pharynx, larynx, lungs, female breast, stomach, pancreas, liver, gallbladder and colorectum. A large prospective cohort study followed women for 7 years and found light to moderate drinking of 7–14 drinks/week was associated with increased risk of all cancers (Relative Risk=1.05, 95% CI 1.03 to 1.07).1 However, the associations of all cancers and only alcohol-related cancer with light to moderate drinking (eg, up to 2 drinks/day for men and 1 drink/day for women per US Dietary Guideline) are not as clear in the USA.To assess the risk of all cancers and all alcohol-related cancers associated with levels of alcohol consumption with a focus on … ER -