TY - JOUR T1 - Treatment for chronic <em>Strongyloides stercoralis</em> infection: moderate-to-low evidence shows that ivermectin is more effective and tolerable than albendazole and thiabendazole, respectively JF - Evidence Based Medicine JO - Evid Based Med SP - 102 LP - 102 DO - 10.1136/ebmed-2016-110417 VL - 21 IS - 3 AU - Dora Buonfrate AU - Federico Gobbi Y1 - 2016/06/01 UR - http://ebm.bmj.com/content/21/3/102.abstract N2 - Commentary on: Henriquez-Camacho C, Gotuzzo E, Echevarria J, et al. Ivermectin versus albendazole or thiabendazole for Strongyloides stercoralis infection. Cochrane Database Syst Rev 2016;1:CD007745.Hundreds of millions of people around the world are estimated to be infected by Strongyloides stercoralis.1 Strongyloidiasis is a soil-transmitted helminthiasis that can persist indefinitely in the infected host if not adequately treated, because of a peculiar autoinfective cycle. Chronic infection is characterised by non-specific symptoms of variable intensity (asymptomatic infection can also occur), mainly relating to the gastrointestinal tract. However, strongyloidiasis is particularly relevant because it can cause a severe syndrome in immunocompromised patients (hyperinfection/dissemination), associated with high mortality.2 Therefore, all infected patients, irrespective of presence of symptoms, should receive a treatment that can guarantee a cure, in order to avoid … ER -