TY - JOUR T1 - Physical, nutritional, cognitive and combination interventions reduce frailty in community-dwelling prefrail and frail older people JF - Evidence Based Medicine JO - Evid Based Med SP - 142 LP - 142 DO - 10.1136/ebmed-2016-110425 VL - 21 IS - 4 AU - Nicola Fairhall Y1 - 2016/08/01 UR - http://ebm.bmj.com/content/21/4/142.abstract N2 - Commentary on: Ng TP, Feng L, Nyunt MS, et al. Nutritional, physical, cognitive, and combination interventions and frailty reversal among older adults: a randomized controlled trial. Am J Med 2015;128:1225–36.e1.OpenUrlCrossRefPubMedFrailty is a common and costly problem. Recent research has enhanced our understanding of the aetiology, diagnosis and impact of frailty, yet the next step is to identify and evaluate interventions that target remediable aspects of frailty. Preventing frailty in people who are prefrail and ameliorating frailty in those already frail, has the potential to reduce poor health outcomes associated with frailty, such as disability, falling, hospitalisation and institutionalisation. To date, few studies have specifically recruited frail individuals or targeted frailty as an outcome. This study examined the effect of four intervention programmes versus usual care on degree of frailty in older people.This was a randomised controlled trial conducted in community-dwelling prefrail and frail volunteers aged 65 years … ER -