TY - JOUR T1 - Intensive treatment of hypertension to a SBP <120 mm Hg in patients aged 75 and over reduces mortality and cardiovascular events JF - Evidence Based Medicine JO - Evid Based Med SP - 30 LP - 30 DO - 10.1136/ebmed-2016-110536 VL - 22 IS - 1 AU - Michael A Weber Y1 - 2017/03/01 UR - http://ebm.bmj.com/content/22/1/30.abstract N2 - Commentary on: Williamson JD, Supiano MA, Applegate WB, et al. Intensive vs standard blood pressure control and cardiovascular disease outcomes in adults aged ≥75 years. A randomized clinical trial. JAMA 2016;315:2673–82OpenUrlCrossRefPubMed.There is uncertainty regarding optimal blood pressure (BP) targets in treating hypertension. Most recent guidelines have recommended a systolic target of <140 mm Hg. The Systolic Blood Pressure Intervention Trial (SPRINT) compared cardiovascular (CV) outcomes in non-diabetic hypertensive patients randomised to standard (systolic blood pressure (SBP) <140 mm Hg) or intensive treatment (<120 mm Hg).1 Composite CV events and total mortality were significantly reduced with intensive treatment. A prespecified analysis evaluated older patients (≥75) and has now been published.SPRINT compared outcomes with treatment targets of <120 mm Hg and <140 mm Hg in hypertensive patients at medium/high CV risk identified by previous CV events (except stroke), high Framingham risk … ER -