TY - JOUR T1 - Intensive blood pressure-lowering reduces mortality and cardiovascular events in older people JF - BMJ Evidence-Based Medicine JO - BMJ EBM SP - 72 LP - 73 DO - 10.1136/bmjebm-2017-110803 VL - 23 IS - 2 AU - Emily Atkins Y1 - 2018/04/01 UR - http://ebm.bmj.com/content/23/2/72.abstract N2 - Commentary on: Weiss J, Freeman M, Low A, et al. Benefits and harms of intensive blood pressure treatment in adults aged 60 years or older: a systematic review and meta-analysis. Ann Intern Med 2017;166:419–429.There has been debate around blood pressure (BP)-lowering targets for older people, with concerns about adverse effects (AEs) such as falls and cognitive changes. The 2014 Eighth Joint National Committee (JNC8) guidelines suggested a less intensive systolic BP (SBP) target of <150 mm Hg for people aged ≥60 years,1 while the 2017 American College of Cardiology/American Heart Association (ACC/ AHA) guidelines recommend target SBP of <130 mm Hg for community-dwelling ambulant adults aged ≥65 years with an average SBP of >130 mm Hg, the same target as those <65 years with high-risk or established cardiovascular disease.2 This change is, in part, because of the strongly positive results seen in elderly participants in the Systolic Blood Pressure Intervention Trial (SPRINT). … ER -