Hormone therapy (HT) v control (placebo, no HT, or calcium supplements) for postmenopausal women*

Outcome at mean 4.5 yearsNumber of trials (n)Weighted event ratesOdds Ratio (95% CI)RRR (CI)NNT (CI)
*Abbreviations defined in glossary; weighted event rates, RRR, RRI, NNT, NNH, and CI calculated from data in article using a random effects model. †Calculated from data in article using odds ratios.
Total mortality
    All ages30 (26 708)4.0% v 4.0%0.98 (0.87 to 1.12)2% (−10 to 13)Not significant
    Mean age <60 years17 (4141)2.7% v 4.3%0.61 (0.39 to 0.95)38% (5 to 60)61 (39 to 481)†
RRI (CI)NNH
    Mean age >60 years13 (22 567)4.0% v 3.9%1.03 (0.9 to 1.18)3% (−9 to 17)Not significant