Association between medication use and hospital admission for lithium toxicity in older persons*
Medication exposure | Adjusted relative risk (95% CI) |
---|---|
*Relative risks adjusted for other potential interacting medications, previous admission for lithium toxicity, renal disease, and number of different prescription drugs in the preceding year. | |
Any use of loop diuretics | 1.7 (1.1 to 2.7) |
Any use of angiotensin converting enzyme (ACE) inhibitors | 1.6 (1.1 to 2.3) |
New use of loop diuretics (⩽28 d) | 5.5 (1.9 to 16.1) |
New use of ACE inhibitors (⩽28 d) | 7.6 (2.6 to 22.0) |