Association between medication use and hospital admission for lithium toxicity in older persons*

Medication exposureAdjusted relative risk (95% CI)
*Relative risks adjusted for other potential interacting medications, previous admission for lithium toxicity, renal disease, and number of different prescription drugs in the preceding year.
Any use of loop diuretics1.7 (1.1 to 2.7)
Any use of angiotensin converting enzyme (ACE) inhibitors1.6 (1.1 to 2.3)
New use of loop diuretics (⩽28 d)5.5 (1.9 to 16.1)
New use of ACE inhibitors (⩽28 d)7.6 (2.6 to 22.0)