Topical diclofenac (TD) v vehicle control (VC) or placebo solution for osteoarthritis (OA) of the knee at 28 days*
| Outcomes† | Mean change from baseline | Difference in mean change from baseline (95% CI) | ||
|---|---|---|---|---|
| TD | VC | Placebo | ||
| *CI defined in glossary. Difference in mean change from baseline calculated from data in article. | ||||
| †Measured by the Western Ontario and McMaster Universities OA index pain subscale. | ||||
| Pain | −3.9 | −2.5 | 1.4 (1.2 to 1.5) | |
| −3.9 | −2.5 | 1.4 (1.2 to 1.5) | ||
| Physical function | −11.6 | −5.7 | 5.9 (5.2 to 6.4) | |
| −11.6 | −7.1 | 4.5 (4.0 to 5.4) | ||
| Stiffness | −1.5 | −0.7 | 0.8 (0.7 to 0.8) | |
| −1.5 | −0.6 | 0.9 (0.9 to 0.9) | ||
| Pain in walking | −0.8 | −0.4 | 0.4 (0.4 to 0.5) | |
| −0.8 | −0.6 | 0.2 (0.2 to 0.3) | ||