Antidepressants for increasing smoking cessation rates at ⩾6 months*

ComparisonsNo of comparisonsEvent ratesRBI (95% CI)NNT (CI)
*NRT  =  nicotine replacement therapy. Other abbreviations defined in glossary; weighted event rates, NNT, and CI calculated from data in article using a fixed effects model.
†Event rates are weighted.
Nortriptyline vs placebo417% v 7.0%†146% (58 to 281)10 (7 to 17)
Bupropion v placebo1919% v 10%†83% (61 to 108)12 (9 to 15)
Bupropion + NRT v placebo + NRT122% v 9.8%128% (46 to 256)8 (6 to 17)
Bupropion v NRT118% v 9.8%88% (18 to 198)12 (7 to 50)