Budesonide (BUD) plus formoterol (FORM) both for maintenance and symptom relief (BUD+FORM for both) v fixed dosing using BUD+FORM or a 4 fold higher dose of BUD (BUDH), both with a short acting β2 agonist (SABA) in asthma*
| Outcomes at 1 year | Comparison | Event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| *Abbreviations defined in glossary; RRR, NNT, and CI calculated from Cox proportional hazard ratio in article. | ||||
| ⩾1 severe asthma exacerbation | BUD+FORM for both v BUD+FORM plus SABA | 16% v 27% | 41% (30 to 52) | 10 (8 to 13) |
| BUD+FORM for both v BUDH plus SABA | 16% v 28% | 43% (31 to 53) | 9 (7 to 12) | |