Naltrexone v placebo in alcohol dependence at ⩽3 months*
| Outcomes at ⩽3 months | Number of trials (n) | Weighted event rates | RRR (95% CI) | NNT (CI) | |
|---|---|---|---|---|---|
| Naltrexone | Control | ||||
| *Abbreviations defined in glossary; weighted event rates, RRR, and CI calculated from data in article using a random effects model. | |||||
| Had a relapse or returned to heavy drinking | 7 (822) | 28% | 43% | 36% (18 to 49) | 7 (5 to 13) |
| Returned to drinking | 10 (1014) | 55% | 65% | 13% (0 to 24) | 10 (6 to 100) |
| Discontinued the medication | 18 (1776) | 35% | 43% | 18% (3 to 30) | 13 (7 to 100) |