Risk factor intervention v no intervention for coronary artery disease (CAD)*

Outcomes (follow up range 6 mo to 12 y)Weighted mean decrease (95% CI)
Systolic blood pressure (mm Hg)3.3 (1.9 to 4.7)
Diastolic blood pressure (mm Hg)2.2 (1.3 to 3.1)
Total blood cholesterol level (mmol/l)0.0.16 (0.09 to 0.24)
Weighted event rates
InterventionNo intervention RRR (CI)NNT (CI)
*Random effects model used for all outcomes except CAD mortality. Abbreviations defined in glossary; NNT calculated from data in article.
Smoking prevalence (follow up range 1 to 12 y)34.5%38%10% (2 to 17)29 (14 to 200)
All cause mortality 7.1% 7.2% 5% (−4 to 13)Not significant
CAD mortality 2.5% 2.6% 4% (−4 to 11)Not significant