Interventions from RCTs for the chronic fatigue syndrome*

InterventionsNumber of RCTsNumber of patientsOverall effect (improvement v no difference)
*CBT = cognitive behavioural therapy; RCTs = randomised controlled trials. Intervention duration ranged from 2 weeks to 1 year (mean 16 wks); follow up ranged from 2 weeks to 5 years.
Behavioural88836 v 2
    Graded exercise33503 v 0
    CBT55333 v 2
Immunological94404 v 5
Pharmacological128962 v 10
Supplements51742 v 3
Complementary or alternative2841 v 1