Losartan-based therapy vs atenolol-based therapy in essential hypertension with signs of left ventricular hypertrophy†

OutcomesLosartanAtenololRRR (95% CI)NNT (CI)
†Abbreviations defined in Glossary; RRR, NNT, and CI calculated from data in article.
‡Cardiovascular mortality, stroke, and myocardial infarction.
Composite end point‡11%13%12% (2 to 22)64 (36 to 418)
Stroke5%7%24% (11 to 36)61 (42 to 140)
New-onset diabetes6%8%24% (12 to 36)52 (35 to 108)