Effects of oestrogen plus progestin (Oest + Prog) v placebo on non-cardiovascular disease outcomes in postmenopausal women with coronary heart disease at 6.8 years†
| Events/1000 person y | ||||
|---|---|---|---|---|
| Outcomes | Oest + Prog | Placebo | Adjusted relative hazard (95% CI)‡ | NNH (CI) |
| †Abbreviations defined in glossary; NNH and CI provided by author. | ||||
| ‡Relative hazard calculated using a Cox proportional hazards model with intention to treat analyses and adjusted for some demographic and baseline characteristics. | ||||
| Venous thromboembolism | 5.9 | 2.8 | 2.06 (1.26 to 3.36) | 65 (35 to 187) |
| Biliary tract surgery | 19.1 | 12.9 | 1.44 (1.10 to 1.90) | 32 (19 to 107) |
| Any cancer | 19.7 | 16.5 | 1.19 (0.95 to 1.50) | Not significant |
| Any fracture | 29.7 | 28.4 | 1.07 (0.89 to 1.29) | Not significant |
| Total mortality | 30.6 | 27.8 | 1.08 (0.91 to 1.29) | Not significant |