Effects of oestrogen plus progestin (Oest + Prog) v placebo on non-cardiovascular disease outcomes in postmenopausal women with coronary heart disease at 6.8 years†

Events/1000 person y
OutcomesOest + ProgPlaceboAdjusted relative hazard (95% CI)‡NNH (CI)
†Abbreviations defined in glossary; NNH and CI provided by author.
‡Relative hazard calculated using a Cox proportional hazards model with intention to treat analyses and adjusted for some demographic and baseline characteristics.
Venous thromboembolism 5.9 2.82.06 (1.26 to 3.36)65 (35 to 187)
Biliary tract surgery19.112.91.44 (1.10 to 1.90)32 (19 to 107)
Any cancer19.716.51.19 (0.95 to 1.50)Not significant
Any fracture29.728.41.07 (0.89 to 1.29)Not significant
Total mortality30.627.81.08 (0.91 to 1.29)Not significant