β blockers v placebo in myocardial infarction at ≥6 months*
| Weighted event rates | |||||
|---|---|---|---|---|---|
| Outcomes | Number of trials | β blockers | Placebo | RRI (95% CI) | NNH (CI) |
| Fatigue | 10 | 34% | 30% | 15% (5 to 26) | 31 (20 to 74) |
| Withdrawal because of fatigue | 10 | 1.8% | 0.5% | 163% (16 to 494) | 75 (43 to 308) |
| Sexual dysfunction | 6 | 19% | 17% | 10% (−4 to 25) | Not significant |
| Withdrawal because of sexual dysfunction | 4 | 1.2% | 0.3% | 397% (203 to 716) | 438 per year† |
| Depressive symptoms | 7 | 21.7% | 20.5% | 12% (−11 to 41) | Not significant |
| RRR (CI) | NNT | ||||
|---|---|---|---|---|---|
| *Abbreviations defined in glossary; weighted event rates, NNT, NNH, and CI calculated from data in article using a random effects model. | |||||
| †Data provided by author in article. | |||||
| Withdrawal because of depressive symptoms | 4 | 0.5% | 0.5% | 6% (−101 to 56) | Not significant |