Symptom improvement with antidepressants v placebo for gastrointestinal disorders with 4 to 12 weeks of treatment*

Weighted event rates
Number of studiesAntidepressantsPlacebo RBI (95% CI)NNT (CI)
*Abbreviations defined in glossary; weighted event rates and RBI supplied by authors.
1169%36%192% (120 to 300)4 (3 to 7)