Antihypertensive therapy v placebo in patients ⩾80 years of age with persistent hypertension*
Outcomes at median 1.8 yearsRate per 1000 person-yearsRRR (95% CI)NNT (CI)
AntihypertensivePlacebo
Stroke121830% (−1 to 51)Not significant
Heart failure5.31564% (42 to 78)106 (87 to 162)
Cardiovascular event†345133% (18 to 46)60 (43 to 113)
Death from all causes476020% (5 to 34)82 (49 to 346)
Death from stroke6.51139% (1 to 62)241 (151 to 9396)
Death from cardiovascular cause243123% (−1 to 40)Not significant
Death from cardiac cause6.08.429% (−19 to 58)Not significant
  • *Abbreviations defined in glossary. RRR, NNT, and CI calculated from data in article.

  • †Stroke, myocardial infarction, heart failure, or death from cardiovascular cause.

  • *Abbreviations defined in glossary. RRR, NNT, and CI calculated from data in article.

  • †Stroke, myocardial infarction, heart failure, or death from cardiovascular cause.