Silicone breast implants and the risk for connective tissue diseases (1 study was excluded for methodological problems)
| Diseases | Number of studies | Adjusted relative risk (95% CI) |
|---|---|---|
| *Not significant. | ||
| All connective tissue diseases | 13 | 0.80 (0.62 to 1.04)* |
| Rheumatoid arthritis | 7 | 1.04 (0.72 to 1.51)* |
| Systemic lupus erythematosus | 4 | 0.65 (0.35 to 1.23)* |
| Scleroderma or systemic sclerosis | 4 | 1.01 (0.59 to 1.73)* |
| Sjögren syndrome | 3 | 1.42 (0.65 to 3.11)* |
| Dermatomyositis or polymyositis | 1 | 1.52 (0.97 to 2.37)* |
| Other autoimmune or rheumatic conditions | 6 | 0.96 (0.74 to 1.25)* |