Blood pressure lowering treatment v placebo in older patients with isolated systolic hypertension to prevent any major CVD event per 100 patient years‡

CVD risk groupTreatmentPlaceboRRR (95% CI)NNT (CI)
‡CVD = cardiovascular disease. Other abbreviations defined in glossary; RRR and CIs calculated from data in article, and event rates and CIs for NNT provided by author.
1st quartile1.92.525% (–14 to 51)Not significant
2nd quartile2.63.629% (1 to 49)100 (58 to 2485)
3rd quartile3.05.243% (24 to 57) 48 (35 to 86)
4th quartile4.37.240% (19 to 56) 37 (26 to 77)