Weighted event rates | ||||
---|---|---|---|---|
Outcomes at 3 to 7 years | Aspirin | Control | RRR (95% CI) | NNT (CI) |
Total coronary events | 1.9% | 2.4% | 28% (13 to 39) | 150 (105 to 324) |
CAD mortality | 0.67% | 0.63% | 13% (–9 to 30) | Not significant |
All-cause mortality | 3.5% | 3.4% | 7% (–2 to 16) | Not significant |
RRI (CI) | NNH (CI) | |||
---|---|---|---|---|
*Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article by using a random effects model. | ||||
†Calculated from data in Sudlow C. Primary prevention. Clin Evid 2001;5:63–94. | ||||
Stroke | 1.4% | 1.3% | 2% (–15 to 23) | Not significant |
Major gastrointestinal bleeding† | 0.8% | 0.48% | 69% (40 to 109) | 302 (193 to 528) |
Haemorrhagic stroke† | 0.22% | 0.17% | 40% (–10 to 100) | Not significant |