Anticonvulsant drugs v placebo for pain relief in adults with chronic pain*
| Weighted event rates | |||||
|---|---|---|---|---|---|
| Pain condition | Number of trials | Anticonvulsant | Placebo | RBI (95% CI) | NNT (CI) |
| *Random effects model used for all analyses. Follow up ranged from 5 weeks to 46 months. Abbreviations defined in glossary; RBI, NNT, and CI calculated from data in article. | |||||
| †Event rates not weighted. | |||||
| Trigeminal neuralgia | 4 | 53% | 21% | 106% (−25 to 462) | 4 (2 to 26) |
| Diabetic neuropathy | 3 | 72% | 38% | 83% (30 to 159) | 3 (3 to 5) |
| Post-herpetic neuralgia† | 1 | 43% | 12% | 257% (109 to 511) | 4 (3 to 5) |
| All neuropathic pain | 9 | 57% | 23% | 109% (35 to 221) | 3 (3 to 5) |