Combined antidepressant and benzodiazepine treatment v antidepressants alone for major depression*
| Weighted event rates | ||||
|---|---|---|---|---|
| Outcomes | Combined | Antidepressant alone | RRR (95% CI) | NNT (CI) |
| Dropped out | 22% | 33% | 37% (19 to 51) | 10 (6 to 22) |
| Dropped out because of side effects | 7% | 14% | 48% (14 to 68) | 15 (10 to 40) |
| RBI (CI) | NNT (CI) | |||
|---|---|---|---|---|
| *Abbreviations defined in glossary; RRR, RBI, NNT, and CI calculated from data in article. | ||||
| >50% reduction in depression at 4 weeks | 52% | 37% | 38% (15 to 66) | 7 (5 to 15) |