17β-estradiol v placebo patch for depressive disorders in perimenopausal women§
| Outcomes at 12 weeks | 17β-estradiol | Placebo | RBI (95% CI) | NNT (CI) |
|---|---|---|---|---|
| §BKMI = Blatt-Kupperman Menopausal Index. Other abbreviations defined in glossary; RBI, NNT, and CI calculated from data in article. | ||||
| Remission of depression | 68% | 20% | 71% (38 to 87) | 3 (1 to 5) |
| ≥ 50% decrease from baseline in BKMI score | 68% | 28% | 59% (23 to 80) | 3 (2 to 8) |