Enoxaparin v warfarin for secondary prophylaxis of venous thromboembolism in patients with cancer and venous thromboembolism ‡
Outcomes at 3 months | Enoxaparin | Warfarin | RRR (95% CI) | NNT (CI) |
---|---|---|---|---|
Treatment failure§ | 10% | 21% | 51% (−10 to 78) | Not significant |
Major haemorrhage | 7% | 16% | 56% (−13 to 83) | Not significant |
Fatal haemorrhage | 0% | 8% | 100% (35 to 100) | 13 (7 to 38) |
Mortality | 11% | 23% | 50% (−4.9 to 77) | Not significant |
RRI | NNH | |||
---|---|---|---|---|
‡Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. | ||||
§Treatment failure = recurrent thromboembolism or major haemorrhage. | ||||
Cancer progression | 17% | 13% | 27% (−40 to 170) | Not significant |