Antiemetics v placebo to reduce nausea in pregnancy at up to 20 weeks of gestationâ€
| Outcomes | Number of trials | Weighted event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| Nausea | 12 | 55% v 24% | 66% (43 to 79) | 4 (3 to 6) |
| RRI (CI) | NNH (CI) | |||
|---|---|---|---|---|
| †Abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. Random effects were used for nausea; fixed effects were used for drowsiness or sleepiness. | ||||
| Drowsiness or sleepiness | 4 | 14.6% v 7.3% | 98% (6 to 271) | 14 (8 to 91) |