Test characteristics for diagnosing submucous fibroids (SF), endometrial hyperplasia (EH), or any intrauterine pathology in abnormal uterine bleeding*
| Tests | Outcomes | Number of studies | Sens range | Spec range | +LR | −LR |
|---|---|---|---|---|---|---|
| *SH = sonohysterography; TVUS = transvaginal ultrasonography; Sens = sensitivity; Spec = specificity. Diagnostic terms defined in glossary. LR is reported as pooled summary estimate with 95% CI or as range. | ||||||
| TVUS | All | 10 | 48–100% | 12–100% | 1.0–52 | 0.057–0.79 |
| SF | 9 | 21–100% | 53–100% | 1.6–62 | 0.03–0.80 | |
| EH | 7 | 33–100% | 79–100% | 2.6–95 | 0.04–0.75 | |
| SH | All | 11 | 85–100% | 50–100% | 2.0–80 | 0.12 (0.08 to 0.18) |
| SF | 7 | 57–100% | 96–100% | 30 (18 to 50) | 0.06–0.47 | |
| EH | 4 | 29–80% | 82–100% | 1.6–70 | 0.14–0.87 | |
| Hysteroscopy | All | 3 | 90–97% | 62–93% | 2.6–15 | 0.07 (0.04 to 0.15) |
| SF | 4 | 53–100% | 97–100% | 29 (13 to 65) | 0.08–0.48 | |
| EH | 3 | 90–100% | 97–100% | 93 (42 to 204) | 0.05 (0.02 to 0.14) | |