Surgery and antibiotics v antibiotics alone in children with vesicoureteric reflux*
| Outcomes | Number of RCTs | Weighted event rates | RRR (95% CI) | NNT (CI) |
|---|---|---|---|---|
| *RCTs = randomised controlled trials; UTI = urinary tract infection. Other abbreviations defined in glossary; RRR, RRI, NNT, NNH, and CI calculated from data in article. | ||||
| Febrile UTI at 5 years | 2 | 9.4% v 22% | 57% (30 to 73) | 8 (6 to 18) |
| UTI at 4–5 years | 3 | 36% v 37% | 1% (−26 to 21) | Not significant |
| RRI (CI) | NNH | |||
| UTI at 1–2 years | 4 | 25% v 20% | 6% (−45 to 104) | Not significant |
| Renal parenchymal injury at 2 years | 2 | 60% v 26% | 80% (−83 to 1768) | Not significant |
| Renal parenchymal injury at 5 years | 3 | 44% v 41% | 5% (–15 to 29) | Not significant |