Calcium supplementation v placebo on fractures and bone mineral density (BMD) loss in postmenopausal women*
| Weighted event rates | |||||
|---|---|---|---|---|---|
| Outcomes (follow up) | Number of trials (sample size) | Intervention | Control | RRR (95% CI) | NNT |
| *Abbreviations defined in glossary; event rates, RRR, and CI calculated from data in article using a fixed effects model. | |||||
| †Not significant. | |||||
| Vertebral fractures (2–4 y) | 5 (576) | 14% | 18% | 21% (−13 to 45) | Not significant |
| BMD site | Weighted mean difference in percentage change from baseline BMD (95% CI) | ||||
| Total body (2–4 y) | 4 (358) | 2.05% (0.24 to 3.86) | |||
| Lumbar spine (2 y) | 9 (845) | 1.66% (0.92 to 2.39) | |||
| Lumbar spine (3 or 4 y) | 2 (218) | 1.13% (−0.11 to 2.38)† | |||
| Combined hip (2–4 y) | 8 (830) | 1.64% (0.70 to 2.57) | |||
| Distal radius (2–4 y) | 6 (615) | 1.91% (0.33 to 3.50) | |||