Primary tumour excision with a surrounding margin of 1 cm v 3 cm in high risk malignant melanoma at a median follow up of 60 months*

Outcomes1 cm margin3 cm marginRRI (95% CI)NNH (CI)
*Composite outcome  =  tumour recurrence or all cause mortality. Other abbreviations defined in glossary; event rates, RRI, NNH, and CI calculated from data in article.
†Borderline significance (p = 0.05).
Local, in transit, or nodal tumour recurrence38%32%20% (0 to 43)16 (8 to ∞)†
All cause mortality32%31%6% (−13 to 28)Not significant
Composite outcome49%44%15% (−1 to 30)Not significant