Institute of Medicine standards for developing trustworthy clinical practice guidelines1
| Standard | Criteria |
|---|---|
| Establishing transparency | Explicit and publically accessible process |
| Management of conflict of interest | Guideline members should disclose all potential conflicts and divest when necessary The group should limit the number of members with conflicts |
| Guideline development group composition | The group should be multidisciplinary and balanced Patient and public involvement should be facilitated |
| Clinical practice guidelines—systematic review intersection | Use or commission high-quality systematic reviews |
| Establishing evidence foundations for, and rating strength of, recommendations | Explain reasoning for recommendations Rate the level of confidence and strength of the recommendation |
| Articulation of recommendations | Explicitly detail the recommended action and circumstances for performing a recommended action Strong recommendations should be worded to facilitate compliance evaluations |
| External review | External reviewers should comprise a full spectrum of relevant stakeholders Reviewers’ identities should be kept confidential Responses to reviewer comments should be recorded Draft guidelines should be available for public comment |
| Updating | Regularly monitor literature Plan periodic updates Modify recommendations when important new evidence emerges |