Examples of questions and application of PICO model
| Therapy question from daily clinical round | Application of PICO method for a suitable bibliographical research |
|---|---|
| What is the duration of antibiotic therapy in a patient with bacterial prostatitis? | P patient with bacterial prostatitis |
| I antibiotic therapy | |
| C standard antibiotic duration (2 weeks) vs 4 weeks of treatment | |
| O reduction in recurrence rate of bacterial prostatitis and complications | |
| Aetiology question from daily clinical round | |
| Which are the non-ischaemic causes that can be associated with an increase in troponin level? | P adults |
| I increase in troponin level | |
| C patients without troponin elevation | |
| O accurate diagnosis of ischaemic disease and treatment | |
| Diagnosis question from daily clinical round | |
| Which are diagnostic criteria for diabetes mellitus? | P adults |
| I diabetes symptoms and/or plasma glucose concentration | |
| C differential diagnosis | |
| O prevention of morbidity and mortality of diabetes | |
| Prevention question from daily clinical round | |
| Is the use of statins, as a primary prevention, useful in diabetic patients with atherosclerosis? | P diabetic patients with atherosclerosis |
| I statins as early prevention treatment | |
| C no statins | |
| O reduction in complications and mortality |