Table 1

Summary of published meta-analyses of the association between impaired CYP2D6 function and disease-free survival among patients with breast cancer treated with tamoxifen

AuthorYear publishedNumber of studies includedPopulation(s)Summary
RR (95% CI)
Seruga201010All1.41 (0.94 to 2.10)
Lum201325All1.34 (1.17 to 1.54)
Zeng201320All1.37 (1.12 to 1.69)
Cronin-Fenton201430All2.08 (1.40 to 3.10)
Jung201410All1.60 (1.04 to 2.47)
Province201410All1.25 (1.06 to 1.47)
Lu201715Asian1.79 (1.14 to 2.80)
  • RR, relative risk.