Table 1

Effect of multicomponent interventions presented in figure 1, under the standard NMA, under the additive CNMA model and under the interaction CNMA model, with an interaction term added to components A and C

ΝΜΑCNMA
InterventionTE
(intervention vs UC)
ComponentTE
(component vs UC)
InterventionAdditive modelInteraction model
TE
(intervention vs UC)
TE
(Intervention vs UC)
A+Cd1AdAA+CdA+dCdA+dC+dAC
A+Dd2BdBA+DdA+dDdA+dD
Bd3CdCBdBdB
B+Cd4DdDB+CdB+dCdB+dC
B+Dd5EdEB+DdA+dDdA+dD
A+Bd6UCReferenceA+BdA+dBdA+dB
A+B+Cd7A+B+CdA+dB+dCdA+dB+dC+dAC
A+B+C+Dd8A+B+C+DdA+dB+dC+dDdA+dB+dC+dD+dAC
A+B+Ed9A+B+EdA+dB+dEdA+dB+dE
A+B+DA+B+DdA+dB+dDdA+dB+dD
C+EC+EdC+dEdC+dE
UCReferenceUCReferenceReference
  • CNMA, component network meta-analysis; NMA, network meta-analysis; TE, Treatment Effect; UC, usual care.