Effect of multicomponent interventions presented in figure 1, under the standard NMA, under the additive CNMA model and under the interaction CNMA model, with an interaction term added to components A and C
| ΝΜΑ | CNMA | |||||
| Intervention | TE (intervention vs UC) | Component | TE (component vs UC) | Intervention | Additive model | Interaction model |
| TE (intervention vs UC) | TE (Intervention vs UC) | |||||
| A+C | d1 | A | dA | A+C | dA+dC | dA+dC+dAC |
| A+D | d2 | B | dB | A+D | dA+dD | dA+dD |
| B | d3 | C | dC | B | dB | dB |
| B+C | d4 | D | dD | B+C | dB+dC | dB+dC |
| B+D | d5 | E | dE | B+D | dA+dD | dA+dD |
| A+B | d6 | UC | Reference | A+B | dA+dB | dA+dB |
| A+B+C | d7 | A+B+C | dA+dB+dC | dA+dB+dC+dAC | ||
| A+B+C+D | d8 | A+B+C+D | dA+dB+dC+dD | dA+dB+dC+dD+dAC | ||
| A+B+E | d9 | A+B+E | dA+dB+dE | dA+dB+dE | ||
| A+B+D | – | A+B+D | dA+dB+dD | dA+dB+dD | ||
| C+E | – | C+E | dC+dE | dC+dE | ||
| UC | Reference | UC | Reference | Reference | ||
CNMA, component network meta-analysis; NMA, network meta-analysis; TE, Treatment Effect; UC, usual care.