Table 1

Description of 201 cardiovascular randomised trials

Mean (range) or percentage
Multiple centres93.0%
Active comparator59.2%
Type of intervention
 Pharmaceutical62.7%
 Surgical18.9%
 Imaging1.0%
 Surgical0.5%
 Other16.9%
Funding
 For profit68.7%
 Government24.9%
 Other6.4%
Sample size5234 (500–50,156)
Follow-up (months)22.9 (1–118)
Loss to follow-up (%)2.0 (0–26)
Fragility index24.6 (1–172)
Sample size powered for 25% RRR8274.2 (96–142 644)
Sample size powered for 30% RRR5706.7 (68–96 236)
  • RRR, relative risk reduction.