Table 1

Registered clinical trials for monkeypox antiviral treatments

Trial identificationDesignIntervention and comparisonPopulation characteristicsStatus
NCT02474589RCT phase IIITecovirimat vs placeboHealthy volunteers,
19–80 years.		Completed
Has results
NCT00907803RCT phase IITecovirimat vs placeboHealthy volunteers,
18–75 years.		Completed
Has results
NCT00728689RT phase ITecovirimatHealthy volunteers,
18–50 years		Completed
Has results
NCT04971109RCT phase IIITecovirimat vs placeboHealthy volunteers,
18–80 years		Recruiting
NCT04392739RT phase IVTecovirimat vs placeboHealthy volunteers,
18–50 years., body weight more than 120 kg		Completed
ISRCTN13846827RT phase ITecovirimatHealthy volunteers,
18–50 years.		Active, not recruiting
NCT02080767Expanded accessTecovirimatVirus exposure,
Paediatric and adult		Recruiting
ISRCTN43307947Expanded accessTecovirimatMonkeypox,
Paediatric and adult		Recruiting
NCT03972111RT phase IVTecovirimatVirus exposure and monkeypox,
Paediatric and adult		Recruiting
NCT02080767Expanded accessTecovirimatVirus exposure,
Paediatric and adult		Recruiting
ACTRN12616001657415RCT phase IBrincidofovir vs placeboHealthy volunteers,
18–55 years		Unknow

  • RCT, Randomized Controlled Trial; RT, Randomized Trial.