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Endoscopy 2010; 42(2): 138-147
DOI: 10.1055/s-0029-1243846
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Quality reporting of endoscopic diagnostic studies in gastrointestinal journals: where do we stand on the use of the STARD and CONSORT statements?

M.  Areia1 , 2 , M.  Soares2 , M.  Dinis-Ribeiro2 , 3
  • 1Gastroenterology Department, Portuguese Oncology Institute–Coimbra, Coimbra, Portugal
  • 2CINTESIS/Department of Biostatistics and Medical Informatics, Porto Faculty of Medicine, Porto, Portugal
  • 3Gastroenterology Department, Portuguese Oncology Institute–Porto, Porto, Portugal
Further Information

Publication History

submitted 10 March 2009

accepted after revision 6 October 2009

Publication Date:
05 February 2010 (online)

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Background and study aims: Many papers have been published in the field of diagnostic endoscopy in the last few years. However, there are no reports on their quality. The aim of this study was to evaluate quality in recently published endoscopic articles.

Materials and methods: The study reviewed published articles on diagnostic endoscopy from 1998 to 2008. Quality was assessed and independently quantified by two observers using the STARD (STandards for the Reporting of Diagnostic accuracy studies) and CONSORT (Consolidated Standards for Reporting of Trials) statements. The interobserver proportion of agreement and κ coefficient were estimated.

Results: A total of 120 articles comprising 10 randomized controlled trials and 110 diagnostic accuracy studies were evaluated. Most studies related to colonic polyp detection (30 %) or evaluation of Barrett’s esophagus (29 %). Chromoscopy (45 %), fluorescence (21 %), and narrow-band imaging (14 %) were the technologies most often evaluated. The mean number of items (i. e. standard requirements) fulfilled by the randomized controlled trials was 15.7 ± 2.2 out of 22 while for the diagnostic accuracy studies it was 12.2 ± 3.6 out of 25. Reporting of study results was complete in 90 % of the randomized controlled trials, but only 65 % of the diagnostic accuracy studies presented a cross-table of results. The global proportion of agreement between observers was 97 % in randomized controlled trials and 95 % in diagnostic accuracy studies.

Conclusions: Recent publications in diagnostic endoscopy achieve only medium quality according to the available statements. It seems that it would be useful for authors, reviewers, and editors to be familiar with and apply these statements. The development of a specific checklist for diagnostic endoscopy publications might be helpful toward achieving better quality reporting in the future.

References

  • 1 Bossuyt P M, Reitsma J B, Bruns D E. et al . Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD Initiative.  Ann Intern Med. 2003;  138 40-44
    CrossrefPubMedGoogle Scholar
  • 2 Bossuyt P M, Reitsma J B, Bruns D E. et al . The STARD statement for reporting studies of diagnostic accuracy: explanation and elaboration.  Ann Intern Med. 2003;  138 W1-W12
    CrossrefPubMedGoogle Scholar
  • 3 Moher D, Schulz K F, Altman D G. et al . The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials.  Ann Intern Med. 2001;  134 657-662
    PubMedGoogle Scholar
  • 4 Altman D G, Schulz K F, Moher D. et al . The revised CONSORT statement for reporting randomized trials: explanation and elaboration.  Ann Intern Med. 2001;  134 663-694
    CrossrefPubMedGoogle Scholar
  • 5 Smidt N, Rutjes A W, van der Windt D A. et al . Reproducibility of the STARD checklist: an instrument to assess the quality of reporting of diagnostic accuracy studies.  BMC Med Res Methodol. 2006;  6 12-21
    CrossrefPubMedGoogle Scholar
  • 6 Moher D, Jones A, Lepage L. et al . Use of the CONSORT statement and quality of reports of randomized trials: a comparative before-and-after evaluation.  JAMA. 2001;  285 1992-1995
    CrossrefPubMedGoogle Scholar
  • 7 Bland J M, Altman D G. Statistical methods for assessing agreement between two methods of clinical measurement.  Lancet. 1986;  1 307-310
    PubMedGoogle Scholar
  • 8 Adler A, Pohl H, Papanikolaou I S. et al . A prospective randomised study on narrow-band imaging versus conventional colonoscopy for adenoma detection: does narrow-band imaging induce a learning effect?.  Gut. 2008;  57 59-64
    CrossrefPubMedGoogle Scholar
  • 9 Brooker J C, Saunders B P, Shah S G. et al . Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy: a randomized controlled trial.  Gastrointest Endosc. 2002;  56 333-338
    CrossrefPubMedGoogle Scholar
  • 10 Hurlstone D P, Cross S S, Slater R. et al . Detecting diminutive colorectal lesions at colonoscopy: a randomised controlled trial of pan-colonic versus targeted chromoscopy.  Gut. 2004;  53 376-380
    CrossrefPubMedGoogle Scholar
  • 11 Kiesslich R, Mergener K, Naumann C. et al . Value of chromoendoscopy and magnification endoscopy in the evaluation of duodenal abnormalities: a prospective, randomized comparison.  Endoscopy. 2003;  35 559-563
    Article in Thieme ConnectPubMedGoogle Scholar
  • 12 Kiesslich R, Fritsch J, Holtmann M. et al . Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis.  Gastroenterology. 2003;  124 880-888
    CrossrefPubMedGoogle Scholar
  • 13 Kiesslich R, Goetz M, Lammersdorf K. et al . Chromoscopy-guided endomicroscopy increases the diagnostic yield of intraepithelial neoplasia in ulcerative colitis.  Gastroenterology. 2007;  132 874-882
    CrossrefPubMedGoogle Scholar
  • 14 Konishi K, Kaneko K, Kurahashi T. et al . A comparison of magnifying and nonmagnifying colonoscopy for diagnosis of colorectal polyps: a prospective study.  Gastrointest Endosc. 2003;  57 48-53
    PubMedGoogle Scholar
  • 15 Lapalus M G, Helbert T, Napoleon B. et al . Does chromoendoscopy with structure enhancement improve the colonoscopic adenoma detection rate?.  Endoscopy. 2006;  38 444-448
    Article in Thieme ConnectPubMedGoogle Scholar
  • 16 Le Rhun M, Coron E, Parlier D. et al . High resolution colonoscopy with chromoscopy versus standard colonoscopy for the detection of colonic neoplasia: a randomized study.  Clin Gastroenterol Hepatol. 2006;  4 349-354
    CrossrefPubMedGoogle Scholar
  • 17 Rex D K, Helbig C C. High yields of small and flat adenomas with high-definition colonoscopes using either white light or narrow band imaging.  Gastroenterology. 2007;  133 42-47
    CrossrefPubMedGoogle Scholar
  • 18 Anagnostopoulos G K, Yao K, Kaye P. et al . High-resolution magnification endoscopy can reliably identify normal gastric mucosa, Helicobacter pylori-associated gastritis, and gastric atrophy.  Endoscopy. 2007;  39 202-207
    Article in Thieme ConnectPubMedGoogle Scholar
  • 19 Apel D, Jakobs R, Schilling D. et al . Accuracy of high-resolution chromoendoscopy in prediction of histologic findings in diminutive lesions of the rectosigmoid.  Gastrointest Endosc. 2006;  63 824-828
    CrossrefPubMedGoogle Scholar
  • 20 Bhunchet E, Hatakawa H, Sakai Y. et al . Fluorescein electronic endoscopy: a novel method for detection of early stage gastric cancer not evident to routine endoscopy.  Gastrointest Endosc. 2002;  55 562-571
    CrossrefPubMedGoogle Scholar
  • 21 Bouma B E, Tearney G J, Compton C C. et al . High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography.  Gastrointest Endosc. 2000;  51 467-474
    CrossrefPubMedGoogle Scholar
  • 22 Bourg-Heckly G, Blais J, Padilla J J. et al . Endoscopic ultraviolet-induced autofluorescence spectroscopy of the esophagus: tissue characterization and potential for early cancer diagnosis.  Endoscopy. 2000;  32 756-765
    Article in Thieme ConnectPubMedGoogle Scholar
  • 23 Brand S, Stepp H, Ochsenkühn T. et al . Detection of colonic dysplasia by light-induced fluorescence endoscopy: a pilot study.  Int J Colorectal Dis. 1999;  14 63-68
    CrossrefPubMedGoogle Scholar
  • 24 Brand S, Wang T D, Schomacker K T. et al . Detection of high-grade dysplasia in Barrett’s esophagus by spectroscopy measurement of 5-aminolevulinic acid-induced protoporphyrin IX fluorescence.  Gastrointest Endosc. 2002;  56 479-487
    CrossrefPubMedGoogle Scholar
  • 25 Breyer H P, Silva De Barros S G, Maguilnik I. et al . Does methylene blue detect intestinal metaplasia in Barrett’s esophagus?.  Gastrointest Endosc. 2003;  57 505-509
    CrossrefPubMedGoogle Scholar
  • 26 Calès P, Oberti F, Delmotte J S. et al . Gastric mucosal surface in cirrhosis evaluated by magnifying endoscopy and scanning electronic microscopy.  Endoscopy. 2000;  32 614-623
    Article in Thieme ConnectPubMedGoogle Scholar
  • 27 Canto M I, Setrakian S, Willis J. et al . Methylene blue-directed biopsies improve detection of intestinal metaplasia and dysplasia in Barrett’s esophagus.  Gastrointest Endosc. 2000;  51 560-568
    CrossrefPubMedGoogle Scholar
  • 28 Chang C C, Pan S, Lien G S, Chen . et al . Investigation of the extent of gastric metaplasia in the duodenal bulb by using methylene blue staining.  J Gastroenterol Hepatol. 2001;  16 729-733
    CrossrefPubMedGoogle Scholar
  • 29 Chiu H M, Chang C Y, Chen C C. et al . A prospective comparative study of narrow-band imaging, chromoendoscopy, and conventional colonoscopy in the diagnosis of colorectal neoplasia.  Gut. 2007;  56 373-379
    CrossrefPubMedGoogle Scholar
  • 30 Dave U, Shousha S, Westaby D. Methylene blue staining: is it really useful in Barrett’s esophagus?.  Gastrointest Endosc. 2001;  53 333-335
    CrossrefPubMedGoogle Scholar
  • 31 Dawsey S M, Fleischer D E, Wang G Q. et al . Mucosal iodine staining improves endoscopic visualization of squamous dysplasia and squamous cell carcinoma of the esophagus in Linxian, China.  Cancer. 1998;  83 220-231
    CrossrefPubMedGoogle Scholar
  • 32 De Palma G D, Rega M, Masone S. et al . Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: a single operator study.  World J Gastroenterol. 2006;  12 2402-2405
    PubMedGoogle Scholar
  • 33 Dekker E, van den Broek F J, Reitsma J B. et al . Narrow-band imaging compared with conventional colonoscopy for the detection of dysplasia in patients with longstanding ulcerative colitis.  Endoscopy. 2007;  39 216-221
    Article in Thieme ConnectPubMedGoogle Scholar
  • 34 Dinis-Ribeiro M, da Costa-Pereira A, Lopes C. et al . Magnification chromoendoscopy for the diagnosis of gastric intestinal metaplasia and dysplasia.  Gastrointest Endosc. 2003;  57 498-504
    CrossrefPubMedGoogle Scholar
  • 35 East J E, Suzuki N, Saunders B P. Comparison of magnified pit pattern interpretation with narrow band imaging versus chromoendoscopy for diminutive colonic polyps: a pilot study.  Gastrointest Endosc. 2007;  66 310-316
    CrossrefPubMedGoogle Scholar
  • 36 Egger K, Werner M, Meining A. et al . Biopsy surveillance is still necessary in patients with Barrett’s oesophagus despite new endoscopic imaging techniques.  Gut. 2003;  52 18-23
    CrossrefPubMedGoogle Scholar
  • 37 Eisen G M, Kim C Y, Fleischer D E. et al . High-resolution chromoendoscopy for classifying colonic polyps: a multicenter study.  Gastrointest Endosc. 2002;  55 687-694
    CrossrefPubMedGoogle Scholar
  • 38 Eloubeidi M A, Provenzale D. Does this patient have Barrett’s esophagus? The utility of predicting Barrett’s esophagus at the index endoscopy.  Am J Gastroenterol. 1999;  94 937-943
    CrossrefPubMedGoogle Scholar
  • 39 Endlicher E, Knuechel R, Hauser T. et al . Endoscopic fluorescence detection of low and high grade dysplasia in Barrett’s oesophagus using systemic or local 5-aminolaevulinic acid sensitisation.  Gut. 2001;  48 314-319
    CrossrefPubMedGoogle Scholar
  • 40 Endo T, Awakawa T, Takahashi H. et al . Classification of Barrett’s epithelium by magnifying endoscopy.  Gastrointest Endosc. 2002;  55 641-647
    CrossrefPubMedGoogle Scholar
  • 41 Fu K I, Sano Y, Kato S. et al . Chromoendoscopy using indigo carmine dye spraying with magnifying observation is the most reliable method for differential diagnosis between non-neoplastic and neoplastic colorectal lesions: a prospective study.  Endoscopy. 2004;  36 1089-1093
    Article in Thieme ConnectPubMedGoogle Scholar
  • 42 Fujiya M, Saitoh Y, Nomura M. et al . Minute findings by magnifying colonoscopy are useful for the evaluation of ulcerative colitis.  Gastrointest Endosc. 2002;  56 535-542
    CrossrefPubMedGoogle Scholar
  • 43 Gangarosa L M, Halter S, Mertz H. Methylene blue staining and endoscopic ultrasound evaluation of Barrett’s esophagus with low-grade dysplasia.  Dig Dis Sci. 2000;  45 225-229
    CrossrefPubMedGoogle Scholar
  • 44 Guelrud M, Herrera I. Acetic acid improves identification of remnant islands of Barrett’s epithelium after endoscopic therapy.  Gastrointest Endosc. 1998;  47 512-515
    CrossrefPubMedGoogle Scholar
  • 45 Guelrud M, Herrera I, Essenfeld H. et al . Enhanced magnification endoscopy: a new technique to identify specialized intestinal metaplasia in Barrett’s esophagus.  Gastrointest Endosc. 2001;  53 559-565
    CrossrefPubMedGoogle Scholar
  • 46 Guelrud M, Herrera I, Essenfeld H. et al . Intestinal metaplasia of the gastric cardia: a prospective study with enhanced magnification endoscopy.  Am J Gastroenterol. 2002;  97 584-589
    CrossrefPubMedGoogle Scholar
  • 47 Hamamoto Y, Endo T, Nosho K. et al . Usefulness of narrow-band imaging endoscopy for diagnosis of Barrett’s esophagus.  J Gastroenterol. 2004;  39 14-20
    CrossrefPubMedGoogle Scholar
  • 48 Hurlstone D P, Cross S S, Brown S. et al . A prospective evaluation of high-magnification chromoscopic colonoscopy in predicting completeness of EMR.  Gastrointest Endosc. 2004;  59 642-650
    CrossrefPubMedGoogle Scholar
  • 49 Hurlstone D P, Cross S S, Adam I. et al . Efficacy of high magnification chromoscopic colonoscopy for the diagnosis of neoplasia in flat and depressed lesions of the colorectum: a prospective analysis.  Gut. 2004;  53 284-290
    CrossrefPubMedGoogle Scholar
  • 50 Hurlstone D P, Karajeh M, Cross S S. et al . The role of high-magnification-chromoscopic colonoscopy in hereditary nonpolyposis colorectal cancer screening: a prospective ”back-to-back” endoscopic study.  Am J Gastroenterol. 2005;  100 2167-2173
    CrossrefPubMedGoogle Scholar
  • 51 Hurlstone D P, Sanders D S, Lobo A J. et al . Indigo carmine-assisted high-magnification chromoscopic colonoscopy for the detection and characterisation of intraepithelial neoplasia in ulcerative colitis: a prospective evaluation.  Endoscopy. 2005;  37 1186-1192
    Article in Thieme ConnectPubMedGoogle Scholar
  • 52 Hurlstone D P, Sanders D S, McAlindon M E. et al . High-magnification chromoscopic colonoscopy in ulcerative colitis: a valid tool for in vivo optical biopsy and assessment of disease extent.  Endoscopy. 2006;  38 1213-1217
    Article in Thieme ConnectPubMedGoogle Scholar
  • 53 Inoue H, Sasajima K, Kaga M. et al . Endoscopic in vivo evaluation of tissue atypia in the esophagus using a newly designed integrated endocytoscope: a pilot trial.  Endoscopy. 2006;  38 891-895
    Article in Thieme ConnectPubMedGoogle Scholar
  • 54 Iseki K, Tatsuta M, Iishi H. et al . Effectiveness of the near-infrared electronic endoscope for diagnosis of the depth of involvement of gastric cancers.  Gastrointest Endosc. 2000;  52 755-762
    CrossrefPubMedGoogle Scholar
  • 55 Kanamori T, Itoh M, Yoshimi N. Pressure dye-spray: a simple and reliable method for differentiating adenomas from hyperplastic polyps in the colon.  Gastrointest Endosc. 2002;  55 695-700
    CrossrefPubMedGoogle Scholar
  • 56 Kara M A, Smits M E, Rosmolen W D. et al . A randomized crossover study comparing light-induced fluorescence endoscopy with standard videoendoscopy for the detection of early neoplasia in Barrett’s esophagus.  Gastrointest Endosc. 2005;  61 671-678
    CrossrefPubMedGoogle Scholar
  • 57 Kara M A, Peters F P, Rosmolen W D. et al . High-resolution endoscopy plus chromoendoscopy or narrow-band imaging in Barrett’s esophagus: a prospective randomized crossover study.  Endoscopy. 2005;  37 929-936
    Article in Thieme ConnectPubMedGoogle Scholar
  • 58 Kara M A, Peters F P, Ten Kate F J. et al . Endoscopic video autofluorescence imaging may improve the detection of early neoplasia in patients with Barrett’s esophagus.  Gastrointest Endosc. 2005;  61 679-685
    CrossrefPubMedGoogle Scholar
  • 59 Kara M A, Ennahachi M, Fockens P. et al . Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett’s esophagus by using narrow band imaging.  Gastrointest Endosc. 2006;  64 155-166
    CrossrefPubMedGoogle Scholar
  • 60 Kara M A, Peters F P, Fockens P. et al . Endoscopic video-autofluorescence imaging followed by narrow band imaging for detecting early neoplasia in Barrett’s esophagus.  Gastrointest Endosc. 2006;  64 176-185
    CrossrefPubMedGoogle Scholar
  • 61 Kato M, Kaise M, Yonezawa J. et al . Autofluorescence endoscopy versus conventional white light endoscopy for the detection of superficial gastric neoplasia: a prospective comparative study.  Endoscopy. 2007;  39 937-941
    Article in Thieme ConnectPubMedGoogle Scholar
  • 62 Kato S, Fujii T, Koba I. et al . Assessment of colorectal lesions using magnifying colonoscopy and mucosal dye spraying: can significant lesions be distinguished?.  Endoscopy. 2001;  33 306-310
    Article in Thieme ConnectPubMedGoogle Scholar
  • 63 Keller R, Winde G, Terpe H J. et al . Fluorescence endoscopy using a fluorescein-labeled monoclonal antibody against carcinoembryonic antigen in patients with colorectal carcinoma and adenoma.  Endoscopy. 2002;  34 801-807
    Article in Thieme ConnectPubMedGoogle Scholar
  • 64 Kiesslich R, vonBergh M, Hahn M. et al . Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon.  Endoscopy. 2001;  33 1001-1006
    Article in Thieme ConnectPubMedGoogle Scholar
  • 65 Kiesslich R, Hahn M, Herrmann G. et al . Screening for specialized columnar epithelium with methylene blue: chromoendoscopy in patients with Barrett’s esophagus and a normal control group.  Gastrointest Endosc. 2001;  53 47-52
    CrossrefPubMedGoogle Scholar
  • 66 Kiesslich R, Burg J, Vieth M. et al . Confocal laser endoscopy for diagnosing intraepithelial neoplasias and colorectal cancer in vivo.  Gastroenterology. 2004;  127 706-713
    CrossrefPubMedGoogle Scholar
  • 67 Kiesslich R, Gossner L, Goetz M. et al . In vivo histology of Barrett’s esophagus and associated neoplasia by confocal laser endomicroscopy.  Clin Gastroenterol Hepatol. 2006;  4 979-987
    CrossrefPubMedGoogle Scholar
  • 68 Kimura T, Muguruma N, Ito S. et al . Infrared fluorescence endoscopy for the diagnosis of superficial gastric tumors.  Gastrointest Endosc. 2007;  66 37-43
    CrossrefPubMedGoogle Scholar
  • 69 Kobayashi M, Tajiri H, Seike E. et al . Detection of early gastric cancer by a real-time autofluorescence imaging system.  Cancer Lett. 2001;  165 155-159
    CrossrefPubMedGoogle Scholar
  • 70 Kouklakis G S, Kountouras J, Dokas S M. et al . Methylene blue chromoendoscopy for the detection of Barrett’s esophagus in a Greek cohort.  Endoscopy. 2003;  35 383-387
    Article in Thieme ConnectPubMedGoogle Scholar
  • 71 Kumagai Y, Monma K, Kawada K. Magnifying chromoendoscopy of the esophagus: in-vivo pathological diagnosis using an endocytoscopy system.  Endoscopy. 2004;  36 590-594
    Article in Thieme ConnectPubMedGoogle Scholar
  • 72 Kunihiro M, Tanaka S, Sumii M. et al . Magnifying colonoscopic features of ulcerative colitis reflect histologic inflammation.  Inflamm Bowel Dis. 2004;  10 737-744
    CrossrefPubMedGoogle Scholar
  • 73 Lee J H, Kim J W, Cho Y K. et al . Detection of colorectal adenomas by routine chromoendoscopy with indigocarmine.  Am J Gastroenterol. 2003;  98 1284-1288
    CrossrefPubMedGoogle Scholar
  • 74 Loffeld R J. Diagnostic value of endoscopic signs of gastritis: with special emphasis to nodular antritis.  Neth J Med. 1999;  54 96-100
    CrossrefPubMedGoogle Scholar
  • 75 Machida H, Sano Y, Hamamoto Y. et al . Narrow-band imaging in the diagnosis of colorectal mucosal lesions: a pilot study.  Endoscopy. 2004;  36 1094-1098
    Google Scholar
  • 76 Mataki N, Nagao S, Kawaguchi A. et al . Clinical usefulness of a new infrared videoendoscope system for diagnosis of early stage gastric cancer.  Gastrointest Endosc. 2003;  57 336-342
    CrossrefPubMedGoogle Scholar
  • 77 Matsumoto T, Nakamura S, Jo Y. et al . Chromoscopy might improve diagnostic accuracy in cancer surveillance for ulcerative colitis.  Am J Gastroenterol. 2003;  98 1827-1833
    CrossrefPubMedGoogle Scholar
  • 78 Matsumoto T, Kudo T, Jo Y. et al . Magnifying colonoscopy with narrow band imaging system for the diagnosis of dysplasia in ulcerative colitis: a pilot study.  Gastrointest Endosc. 2007;  66 957-965
    CrossrefPubMedGoogle Scholar
  • 79 Mayinger B, Horner P, Jordan M. et al . Light-induced autofluorescence spectroscopy for tissue diagnosis of GI lesions.  Gastrointest Endosc. 2000;  52 395-400
    CrossrefPubMedGoogle Scholar
  • 80 Mayinger B, Neidhardt S, Reh H. et al . Fluorescence induced with 5-aminolevulinic acid for the endoscopic detection and follow-up of esophageal lesions.  Gastrointest Endosc. 2001;  54 572-578
    CrossrefPubMedGoogle Scholar
  • 81 Mayinger B, Oezturk Y, Stolte M. et al . Evaluation of sensitivity and inter- and intra-observer variability in the detection of intestinal metaplasia and dysplasia in Barrett’s esophagus with enhanced magnification endoscopy.  Scand J Gastroenterol. 2006;  41 349-356
    CrossrefPubMedGoogle Scholar
  • 82 Meining A, Rösch T, Kiesslich R. et al . Inter- and intra-observer variability of magnification chromoendoscopy for detecting specialized intestinal metaplasia at the gastroesophageal junction.  Endoscopy. 2004;  36 160-164
    Article in Thieme ConnectPubMedGoogle Scholar
  • 83 Messmann H, Endlicher E, Freunek G. et al . Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation.  Gut. 2003;  52 1003-1007
    CrossrefPubMedGoogle Scholar
  • 84 Morales T G, Bhattacharyya A, Camargo E. et al . Methylene blue staining for intestinal metaplasia of the gastric cardia with follow-up for dysplasia.  Gastrointest Endosc. 1998;  48 26-31
    CrossrefPubMedGoogle Scholar
  • 85 Muto M, Hironaka S, Nakane M. et al . Association of multiple Lugol-voiding lesions with synchronous and metachronous esophageal squamous cell carcinoma in patients with head and neck cancer.  Gastrointest Endosc. 2002;  56 517-521
    CrossrefPubMedGoogle Scholar
  • 86 Mycek M A, Schomacker K T, Nishioka N S. Colonic polyp differentiation using time-resolved autofluorescence spectroscopy.  Gastrointest Endosc. 1998;  48 390-394
    CrossrefPubMedGoogle Scholar
  • 87 Nakagawa S, Kato M, Shimizu Y. et al . Relationship between histopathologic gastritis and mucosal microvascularity: observations with magnifying endoscopy.  Gastrointest Endosc. 2003;  58 71-75
    CrossrefPubMedGoogle Scholar
  • 88 Nakayoshi T, Tajiri H, Matsuda K. et al . Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video).  Endoscopy. 2004;  36 1080-1084
    Article in Thieme ConnectPubMedGoogle Scholar
  • 89 Namihisa A, Miwa H, Watanabe H. et al . A new technique: light-induced fluorescence endoscopy in combination with pharmacoendoscopy.  Gastrointest Endosc. 2001;  53 343-348
    PubMedGoogle Scholar
  • 90 Niepsuj K, Niepsuj G, Cebula W. et al . Autofluorescence endoscopy for detection of high-grade dysplasia in short-segment Barrett’s esophagus.  Gastrointest Endosc. 2003;  58 715-719
    CrossrefPubMedGoogle Scholar
  • 91 Ohkawa A, Miwa H, Namihisa A. et al . Diagnostic performance of light-induced fluorescence endoscopy for gastric neoplasms.  Endoscopy. 2004;  36 515-521
    Article in Thieme ConnectPubMedGoogle Scholar
  • 92 Ortner M A, Ebert B, Hein E. et al . Time gated fluorescence spectroscopy in Barrett’s oesophagus.  Gut. 2003;  52 28-33
    CrossrefPubMedGoogle Scholar
  • 93 Pohl H, Koch M, Khalifa A. et al . Evaluation of endocytoscopy in the surveillance of patients with Barrett’s esophagus.  Endoscopy. 2007;  39 492-496
    Article in Thieme ConnectPubMedGoogle Scholar
  • 94 Poneros J M, Brand S, Bouma B E. et al . Diagnosis of specialized intestinal metaplasia by optical coherence tomography.  Gastroenterology. 2001;  120 7-12
    CrossrefPubMedGoogle Scholar
  • 95 Ragunath K, Krasner N, Raman V S. et al . A randomized, prospective cross-over trial comparing methylene blue-directed biopsy and conventional random biopsy for detecting intestinal metaplasia and dysplasia in Barrett’s esophagus.  Endoscopy. 2003;  35 998-1003
    Article in Thieme ConnectPubMedGoogle Scholar
  • 96 Rastogi A, Bansal A, Wani S. et al . Narrow-band imaging colonoscopy – a pilot feasibility study for the detection of polyps and correlation of surface patterns with polyp histologic diagnosis.  Gastrointest Endosc. 2008;  67 280-286
    CrossrefPubMedGoogle Scholar
  • 97 Raţiu N, Rath H C, Büttner R. et al . The effect of chromoendoscopy on the diagnostic improvement of gastric ulcers by endoscopists with different levels of experience.  Rom J Gastroenterol. 2005;  14 239-244
    PubMedGoogle Scholar
  • 98 Réaud S, Croue A, Boyer J. Diagnostic accuracy of magnifying chromoendoscopy with detection of intestinal metaplasia and dysplasia using acetic acid in Barrett’s esophagus.  Gastroenterol Clin Biol. 2006;  30 217-223
    CrossrefPubMedGoogle Scholar
  • 99 Redéen S, Petersson F, Jönsson K A. et al . Relationship of gastroscopic features to histological findings in gastritis and Helicobacter pylori infection in a general population sample.  Endoscopy. 2003;  35 946-950
    Article in Thieme ConnectPubMedGoogle Scholar
  • 100 Rutter M D, Saunders B P, Schofield G. et al . Pancolonic indigo carmine dye spraying for the detection of dysplasia in ulcerative colitis.  Gut. 2004;  53 256-260
    CrossrefPubMedGoogle Scholar
  • 101 Sada M, Igarashi M, Yoshizawa S. et al . Dye spraying and magnifying endoscopy for dysplasia and cancer surveillance in ulcerative colitis.  Dis Colon Rectum. 2004;  47 1816-1823
    CrossrefPubMedGoogle Scholar
  • 102 Saitoh Y, Obara T, Watari J. et al . Invasion depth diagnosis of depressed type early colorectal cancers by combined use of videoendoscopy and chromoendoscopy.  Gastrointest Endosc. 1998;  48 362-370
    CrossrefPubMedGoogle Scholar
  • 103 Sasajima K, Kudo S E, Inoue H. et al . Real-time in vivo virtual histology of colorectal lesions when using the endocytoscopy system.  Gastrointest Endosc. 2006;  63 1010-1017
    CrossrefPubMedGoogle Scholar
  • 104 Sharma P, Topalovski M, Mayo M S. et al . Methylene blue chromoendoscopy for detection of short-segment Barrett’s esophagus.  Gastrointest Endosc. 2001;  54 289-293
    CrossrefPubMedGoogle Scholar
  • 105 Sharma P, Weston A P, Topalovski M. et al . Magnification chromoendoscopy for the detection of intestinal metaplasia and dysplasia in Barrett’s oesophagus.  Gut. 2003;  52 24-27
    CrossrefPubMedGoogle Scholar
  • 106 Sharma P, Bansal A, Mathur S. et al . The utility of a novel narrow band imaging endoscopy system in patients with Barrett’s esophagus.  Gastrointest Endosc. 2006;  64 167-175
    CrossrefPubMedGoogle Scholar
  • 107 Sharma P, Marcon N, Wani S. et al . Non-biopsy detection of intestinal metaplasia and dysplasia in Barrett’s esophagus: a prospective multicenter study.  Endoscopy. 2006;  38 1206-1212
    Article in Thieme ConnectPubMedGoogle Scholar
  • 108 Shimizu Y, Tukagoshi H, Fujita M. et al . Endoscopic screening for early esophageal cancer by iodine staining in patients with other current or prior primary cancers.  Gastrointest Endosc. 2001;  53 1-5
    CrossrefPubMedGoogle Scholar
  • 109 Smith A D, Graham I, Rose J D. A prospective endoscopic study of scalloped folds and grooves in the mucosa of the duodenum as signs of villous atrophy.  Gastrointest Endosc. 1998;  47 461-465
    CrossrefPubMedGoogle Scholar
  • 110 Su M Y, Ho Y P, Chen P C. et al . Magnifying endoscopy with indigo carmine contrast for differential diagnosis of neoplastic and non neoplastic colonic polyps.  Dig Dis Sci. 2004;  49 1123-1127
    CrossrefPubMedGoogle Scholar
  • 111 Su M Y, Hsu C M, Ho Y P. et al . Comparative study of conventional colonoscopy, chromoendoscopy, and narrow-band imaging systems in differential diagnosis of neoplastic and nonneoplastic colonic polyps.  Am J Gastroenterol. 2006;  101 2711-2716
    CrossrefPubMedGoogle Scholar
  • 112 Tajiri H, Doi T, Endo H. et al . Routine endoscopy using a magnifying endoscope for gastric cancer diagnosis.  Endoscopy. 2002;  34 772-777
    Article in Thieme ConnectPubMedGoogle Scholar
  • 113 Tischendorf J J, Wasmuth H E, Koch A. et al . Value of magnifying chromoendoscopy and narrow band imaging (NBI) in classifying colorectal polyps: a prospective controlled study.  Endoscopy. 2007;  39 1092-1096
    Article in Thieme ConnectPubMedGoogle Scholar
  • 114 Togashi K, Konishi F, Ishizuka T. et al . Efficacy of magnifying endoscopy in the differential diagnosis of neoplastic and non-neoplastic polyps of the large bowel.  Dis Colon Rectum. 1999;  42 1602-1608
    CrossrefPubMedGoogle Scholar
  • 115 Togashi K, Hewett D G, Whitaker D A. et al . The use of acetic acid in magnification chromocolonoscopy for pit pattern analysis of small polyps.  Endoscopy. 2006;  38 613-616
    Article in Thieme ConnectPubMedGoogle Scholar
  • 116 Toyoda H, Rubio C, Befrits R. et al . Detection of intestinal metaplasia in distal esophagus and esophagogastric junction by enhanced-magnification endoscopy.  Gastrointest Endosc. 2004;  59 15-21
    CrossrefPubMedGoogle Scholar
  • 117 Tung S Y, Wu C S, Su M Y. Magnifying colonoscopy in differentiating neoplastic from nonneoplastic colorectal lesions.  Am J Gastroenterol. 2001;  96 2628-2632
    CrossrefPubMedGoogle Scholar
  • 118 Vo-Dinh T, Panjehpour M, Overholt B F. Laser-induced fluorescence for esophageal cancer and dysplasia diagnosis.  Ann N Y Acad Sci. 1998;  838 116-122
    CrossrefPubMedGoogle Scholar
  • 119 Wallace M B, Perelman L T, Backman V. et al . Endoscopic detection of dysplasia in patients with Barrett’s esophagus using light-scattering spectroscopy.  Gastroenterology. 2000;  119 677-682
    CrossrefPubMedGoogle Scholar
  • 120 Wang T D, Crawford J M, Feld M S. et al . In vivo identification of colonic dysplasia using fluorescence endoscopic imaging.  Gastrointest Endosc. 1999;  49 447-455
    CrossrefPubMedGoogle Scholar
  • 121 Wo J M, Ray M B, Mayfield-Stokes S. et al . Comparison of methylene blue-directed biopsies and conventional biopsies in the detection of intestinal metaplasia and dysplasia in Barrett’s esophagus: a preliminary study.  Gastrointest Endosc. 2001;  54 294-301
    CrossrefPubMedGoogle Scholar
  • 122 Yagi K, Nakamura A, Sekine A. Comparison between magnifying endoscopy and histological, culture and urease test findings from the gastric mucosa of the corpus.  Endoscopy. 2002;  34 376-381
    Article in Thieme ConnectPubMedGoogle Scholar
  • 123 Yagi K, Nakamura A, Sekine A. Characteristic endoscopic and magnified endoscopic findings in the normal stomach without Helicobacter pylori infection.  J Gastroenterol Hepatol. 2002;  17 39-45
    CrossrefPubMedGoogle Scholar
  • 124 Yagi K, Nakamura A, Sekine A. Accuracy of magnifying endoscopy with methylene blue in the diagnosis of specialized intestinal metaplasia and short-segment Barrett’s esophagus in Japanese patients without Helicobacter pylori infection.  Gastrointest Endosc. 2003;  58 189-195
    CrossrefPubMedGoogle Scholar
  • 125 Yao K, Yao T, Matsui T. et al . Hemoglobin content in intramucosal gastric carcinoma as a marker of histologic differentiation: a clinical application of quantitative electronic endoscopy.  Gastrointest Endosc. 2000;  52 241-245
    CrossrefPubMedGoogle Scholar
  • 126 Yoo H Y, Eustace J A, Verma S. et al . Accuracy and reliability of the endoscopic classification of portal hypertensive gastropathy.  Gastrointest Endosc. 2002;  56 675-680
    CrossrefPubMedGoogle Scholar
  • 127 Yoshida T, Inoue H, Usui S. et al . Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions.  Gastrointest Endosc. 2004;  59 288-295
    CrossrefPubMedGoogle Scholar

M. AreiaMD 

Gastroenterology Department
Portuguese Oncology Institute
Coimbra
Avenida Bissaya Barreto

Apartado 2005
3001-651 Coimbra
Portugal

Fax: +351-239-484317

Email: miguel.areia@netcabo.pt

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