Cancer-associated venous thromboembolism: burden, mechanisms, and management

C Ay, I Pabinger, AT Cohen - Thrombosis and haemostasis, 2017 - thieme-connect.com
Venous thromboembolism (VTE) is a significant health problem in the general population
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …

Assessment of venous thromboembolism risk and the benefits of thromboprophylaxis in medical patients

AT Cohen, R Alikhan, JI Arcelus… - Thrombosis and …, 2005 - thieme-connect.com
Hospitalized patients with acute medical conditions are at significant risk of venous
thromboembolism (VTE): approximately 10–30% of general medical patients may develop …

Venous thromboembolism (VTE) in Europe

AT Cohen, G Agnelli, FA Anderson… - Thrombosis and …, 2007 - thieme-connect.com
Venous thromboembolism (VTE) is often asymptomatic, misdiagnosed, and unrecognized at
death, and there is a lack of routine postmortem examinations. These factors are thought to …

Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients

A Leizorovicz, AT Cohen, AGG Turpie, CG Olsson… - Circulation, 2004 - Am Heart Assoc
Background—Considerable variability exists in the use of pharmacological
thromboprophylaxis among acutely ill medical patients, partly because clinically relevant …

Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction)

R Alikhan, R Forster, AT Cohen - Cochrane Database of …, 2014 - cochranelibrary.com
Background Venous thromboembolic disease has been extensively studied in surgical
patients. The benefit of thromboprophylaxis is now generally accepted, but it is medical …

Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study

AT Cohen, VF Tapson, JF Bergmann, SZ Goldhaber… - The lancet, 2008 - thelancet.com
Background Information about the variation in the risk for venous thromboembolism (VTE)
and in prophylaxis practices around the world is scarce. The ENDORSE (Epidemiologic …

Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomised placebo controlled trial

AT Cohen, BL Davidson, AS Gallus, MR Lassen… - Bmj, 2006 - bmj.com
Objective To determine the efficacy and safety of the anticoagulant fondaparinux in older
acute medical inpatients at moderate to high risk of venous thromboembolism. Design …

[HTML][HTML] Andexanet alfa for acute major bleeding associated with factor Xa inhibitors

SJ Connolly, TJ Milling Jr, JW Eikelboom… - … England Journal of …, 2016 - Mass Medical Soc
Background Andexanet alfa (andexanet) is a recombinant modified human factor Xa decoy
protein that has been shown to reverse the inhibition of factor Xa in healthy volunteers …

[HTML][HTML] Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer

D Bergqvist, G Agnelli, AT Cohen, A Eldor… - … England Journal of …, 2002 - Mass Medical Soc
Background Abdominal surgery for cancer carries a high risk of venous thromboembolism,
but the optimal duration of postoperative thromboprophylaxis is unknown. Methods We …

[HTML][HTML] Full study report of andexanet alfa for bleeding associated with factor Xa inhibitors

SJ Connolly, M Crowther, JW Eikelboom… - … England Journal of …, 2019 - Mass Medical Soc
Background Andexanet alfa is a modified recombinant inactive form of human factor Xa
developed for reversal of factor Xa inhibitors. Methods We evaluated 352 patients who had …