Cancer-associated venous thromboembolism: burden, mechanisms, and management
Venous thromboembolism (VTE) is a significant health problem in the general population
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …
but especially in cancer patients. In this review, we discuss the epidemiology and burden of …
Assessment of venous thromboembolism risk and the benefits of thromboprophylaxis in medical patients
AT Cohen, R Alikhan, JI Arcelus… - Thrombosis and …, 2005 - thieme-connect.com
Hospitalized patients with acute medical conditions are at significant risk of venous
thromboembolism (VTE): approximately 10–30% of general medical patients may develop …
thromboembolism (VTE): approximately 10–30% of general medical patients may develop …
Venous thromboembolism (VTE) in Europe
Venous thromboembolism (VTE) is often asymptomatic, misdiagnosed, and unrecognized at
death, and there is a lack of routine postmortem examinations. These factors are thought to …
death, and there is a lack of routine postmortem examinations. These factors are thought to …
Randomized, placebo-controlled trial of dalteparin for the prevention of venous thromboembolism in acutely ill medical patients
A Leizorovicz, AT Cohen, AGG Turpie, CG Olsson… - Circulation, 2004 - Am Heart Assoc
Background—Considerable variability exists in the use of pharmacological
thromboprophylaxis among acutely ill medical patients, partly because clinically relevant …
thromboprophylaxis among acutely ill medical patients, partly because clinically relevant …
Heparin for the prevention of venous thromboembolism in acutely ill medical patients (excluding stroke and myocardial infarction)
Background Venous thromboembolic disease has been extensively studied in surgical
patients. The benefit of thromboprophylaxis is now generally accepted, but it is medical …
patients. The benefit of thromboprophylaxis is now generally accepted, but it is medical …
Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study
AT Cohen, VF Tapson, JF Bergmann, SZ Goldhaber… - The lancet, 2008 - thelancet.com
Background Information about the variation in the risk for venous thromboembolism (VTE)
and in prophylaxis practices around the world is scarce. The ENDORSE (Epidemiologic …
and in prophylaxis practices around the world is scarce. The ENDORSE (Epidemiologic …
Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomised placebo controlled trial
AT Cohen, BL Davidson, AS Gallus, MR Lassen… - Bmj, 2006 - bmj.com
Objective To determine the efficacy and safety of the anticoagulant fondaparinux in older
acute medical inpatients at moderate to high risk of venous thromboembolism. Design …
acute medical inpatients at moderate to high risk of venous thromboembolism. Design …
[HTML][HTML] Andexanet alfa for acute major bleeding associated with factor Xa inhibitors
SJ Connolly, TJ Milling Jr, JW Eikelboom… - … England Journal of …, 2016 - Mass Medical Soc
Background Andexanet alfa (andexanet) is a recombinant modified human factor Xa decoy
protein that has been shown to reverse the inhibition of factor Xa in healthy volunteers …
protein that has been shown to reverse the inhibition of factor Xa in healthy volunteers …
[HTML][HTML] Duration of prophylaxis against venous thromboembolism with enoxaparin after surgery for cancer
Background Abdominal surgery for cancer carries a high risk of venous thromboembolism,
but the optimal duration of postoperative thromboprophylaxis is unknown. Methods We …
but the optimal duration of postoperative thromboprophylaxis is unknown. Methods We …
[HTML][HTML] Full study report of andexanet alfa for bleeding associated with factor Xa inhibitors
Background Andexanet alfa is a modified recombinant inactive form of human factor Xa
developed for reversal of factor Xa inhibitors. Methods We evaluated 352 patients who had …
developed for reversal of factor Xa inhibitors. Methods We evaluated 352 patients who had …