Background: Osteoporosis is a major contributor to the propensity to fracture among older
adults, and various pharmaceuticals are available to treat it. Purpose: To update a review …

Objectives To catalog what is known about the safety of interventions containing
Lactobacillus, Bifidobacterium, Saccharomyces, Streptococcus, Enterococcus, and/or …

Background: Health information exchange (HIE) is increasing in the United States, and it is
incentivized by government policies. Purpose: To systematically review and evaluate …

Objectives Antipsychotic medications are approved by the US Food and Drug Administration
(FDA) for treatment of schizophrenia, bipolar disorder, and for some drugs, depression. We …

Importance: Evidence supports palliative care effectiveness. Given workforce constraints
and the costs of new services, payers and providers need help to prioritize their investments …

Objectives: Substance use disorder (SUD) is a prevalent health issue with serious personal
and societal consequences. This review aims to estimate the effects and safety of …

Context Palliative care continues to be a rapidly growing field aimed at improving quality of
life for patients and their caregivers. Objectives The purpose of this review was to provide a …

Objective Valid, reliable critical appraisal tools advance quality improvement (QI)
intervention impacts by helping stakeholders identify higher quality studies. QI approaches …

Background: Gout is a common type of inflammatory arthritis in patients seen by primary
care physicians. Purpose: To review evidence about treatment of acute gout attacks …

Background In 2009, the Institute of Medicine/Food and Nutrition Board constituted a Dietary
Reference Intakes (DRI) committee to undertake a review of the evidence that had emerged …