User profiles for "author:E O’Toole"

Edel O'Toole

Blizard Institute, Queen Mary University of London
Verified email at qmul.ac.uk
Cited by 9212

Extracellular matrix and keratinocyte migration

EA O'toole - Clinical and experimental dermatology, 2001 - academic.oup.com
We are just beginning to understand some of the cellular mechanisms involved in human
keratinocyte migration on extracellular matrix. Extracellular matrix components have differing …

Harlequin ichthyosis: a review of clinical and molecular findings in 45 cases

…, C Chu, C Mein, D Kelsell, E O'Toole - Archives of …, 2011 - jamanetwork.com
… Analysis and interpretation of data: Rajpopat, Moss, Paige, Fleckman, Mein, Kelsell, and
OToole. Drafting of the manuscript: Rajpopat, Kelsell, and OToole. Critical revision of the …

Matrix metalloproteinases and epidermal wound repair

VL Martins, M Caley, EA O'Toole - Cell and tissue research, 2013 - Springer
Epidermal wound healing is a complex and highly coordinated process where several
different cell types and molecules, such as growth factors and extracellular matrix (ECM) …

Intestinal flora in new-born infants: with a description of a new pathogenic anaerobe, Bacillus difficilis

IC Hall, E O'toole - American journal of diseases of children, 1935 - jamanetwork.com
Following our first article on the bacterial flora of first passage specimens of meconium from
fifty new-born infants 1 we studied the daily microbial changes in the feces of ten normal …

Metalloproteinases and wound healing

MP Caley, VLC Martins, EA O'Toole - Advances in wound care, 2015 - liebertpub.com
Significance: Matrix metalloproteinases (MMPs) are present in both acute and chronic
wounds. They play a pivotal role, with their inhibitors, in regulating extracellular matrix …

Developmental cell programs are co-opted in inflammatory skin disease

…, S Lisgo, AC Villani, J Bacardit, PH Jones, EA O'Toole… - Science, 2021 - science.org
INTRODUCTION Human skin provides vital protection from water loss and from external insult
through structural adaptations and interplay with the innate and adaptive immune systems…

Piecemeal Microautophagy of Nucleus in Saccharomyces cerevisiae

…, E Kvam, E O'Toole… - Molecular biology of …, 2003 - Am Soc Cell Biol
Nucleus-vacuole (NV) junctions in Saccharomyces cerevisiae are formed through specific
interactions between Vac8p on the vacuole membrane and Nvj1p in the nuclear envelope. …

Three-dimensional ultrastructural analysis of the Saccharomyces cerevisiae mitotic spindle.

M Winey, CL Mamay, ET O'Toole… - The Journal of cell …, 1995 - rupress.org
The three dimensional organization of microtubules in mitotic spindles of the yeast
Saccharomyces cerevisiae has been determined by computer-aided reconstruction from electron …

A selective activity-dependent requirement for dynamin 1 in synaptic vesicle endocytosis

…, P Ariel, S Paradise, E O'toole, R Flavell, O Cremona… - Science, 2007 - science.org
Dynamin 1 is a neuron-specific guanosine triphosphatase thought to be critically required for
the fission reaction of synaptic vesicle endocytosis. Unexpectedly, mice lacking dynamin 1 …

[PDF][PDF] Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits

…, O Destaing, G Ko, J Takasaki, O Cremona, E O'Toole… - Developmental cell, 2009 - cell.com
The GTPase dynamin, a key player in endocytic membrane fission, interacts with numerous
proteins that regulate actin dynamics and generate/sense membrane curvature. To …