The first two oral antivirals, molnupiravir and nirmatrelvir–ritonavir, are now becoming
available in many countries. These medicines will be indicated to treat mild-to-moderate …

Large-scale deployment of COVID-19 vaccines will seriously affect the ongoing phases 2
and 3 randomised placebo-controlled trials assessing SARS-CoV-2 vaccine candidates …

Introduction Pragmatic randomized controlled trials (RCTs) mimic usual clinical practice and
they are critical to inform decision-making by patients, clinicians and policy-makers in real …

ABSTRACT A geographical analysis of how commonly prescribed oral antibiotics are
quantitatively and qualitatively responsible for the different local rates of erythromycin and …

PURPOSE: Arterial hypertension is an insulin-resistant condition that has been associated
with an increased incidence of diabetes. We assessed the prevalence of glucose …

ABSTRACT A nationwide multicenter susceptibility surveillance study (Susceptibility to the
Antimicrobials Used in the Community in España [SAUCE] project), SAUCE-4, including …

The World Medical Association started revisions to the Declaration of Helsinki in 2022 and it
will have to address numerous issues that have arisen in research ethics since the last 2013 …

Streptococcus pneumoniae resistance to penicillin and erythromycin in relation to β-lactam
and macrolide consumption in Spain over 19 years (1979–1997) was studied from …

A 1-year retrospective multicentre study was performed to identify factors influencing
hospital length of stay (LOS) and mortality of patients (n= 3233) admitted to hospital because …

Introduction The preclinical phase of Alzheimer's disease (AD) is optimal for identifying early
pathophysiological events and developing prevention programs, which are shared aims of …