Executive summary Improving the care of patients with community-acquired pneumonia
(CAP) in South Africa is particularly important because of the high burden of disease and the …

Importance Extended-spectrum β-lactamases mediate resistance to third-generation
cephalosporins (eg, ceftriaxone) inEscherichia coliandKlebsiella pneumoniae. Significant …

Antibiotic resistance has increased worldwide to the extent that it is now regarded as a
global public health crisis. Interventions to reduce excessive antibiotic prescribing to patients …

Tuberculosis (TB) is the leading cause of preventable death in HIV-positive patients, and yet
often remains undiagnosed and untreated. Chest x-ray is often used to assist in diagnosis …

Background The size of the west African Ebola virus disease outbreak led to the urgent
establishment of Ebola holding unit facilities for isolation and diagnostic testing of patients …

Importance Practice guidelines often provide recommendations in which the strength of the
recommendation is dissociated from the quality of the evidence. Objective To create a …

Introduction The prognosis of patients with HIV in Africa has improved with the widespread
use of antiretroviral therapy (ART) but these successes are threatened by low rates of long …

Background. Education of medical students has been identified by the World Health
Organization as an important aspect of antibiotic resistance (ABR) containment. Surveys …

Background Antibiotic consumption is a major driver of bacterial resistance. To address the
increasing burden of multi-drug resistant bacterial infections, antibiotic stewardship …

Pneumocystis jirovecii is a ubiquitous opportunistic fungus that can cause life-threatening
pneumonia. People with HIV (PWH) who have low CD4 counts are one of the populations at …