User profiles for "author:Vidu Garg"
Vidu GargDirector, Center for Cardiovascular Research, Nationwide Children's Hospital Verified email at nationwidechildrens.org Cited by 9200 |
Genetic basis for congenital heart disease: revisited: a scientific statement from the American Heart Association
This review provides an updated summary of the state of our knowledge of the genetic
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …
contributions to the pathogenesis of congenital heart disease. Since 2007, when the initial …
Mutations in NOTCH1 cause aortic valve disease
V Garg, AN Muth, JF Ransom, MK Schluterman… - Nature, 2005 - nature.com
Calcification of the aortic valve is the third leading cause of heart disease in adults. The
incidence increases with age, and it is often associated with a bicuspid aortic valve present …
incidence increases with age, and it is often associated with a bicuspid aortic valve present …
Molecular genetics of aortic valve disease
V Garg - Current opinion in cardiology, 2006 - journals.lww.com
The recent genetic and biochemical findings provide novel insights into the molecular and
genetic basis for aortic valve dysmorphogenesis and calcification. Future studies focusing …
genetic basis for aortic valve dysmorphogenesis and calcification. Future studies focusing …
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
V Garg, IS Kathiriya, R Barnes, MK Schluterman… - Nature, 2003 - nature.com
Congenital heart defects (CHDs) are the most common developmental anomaly and are the
leading non-infectious cause of mortality in newborns. Only one causative gene, NKX2-5 …
leading non-infectious cause of mortality in newborns. Only one causative gene, NKX2-5 …
Maternal hyperglycemia and fetal cardiac development: Clinical impact and underlying mechanisms
Congenital heart disease (CHD) is the most common type of birth defect and is both a
significant pediatric and adult health problem, in light of a growing population of survivors …
significant pediatric and adult health problem, in light of a growing population of survivors …
Tbx1, a DiGeorge syndrome candidate gene, is regulated by sonic hedgehog during pharyngeal arch development
V Garg, C Yamagishi, T Hu, IS Kathiriya… - Developmental …, 2001 - Elsevier
Appropriate interactions between the epithelium and adjacent neural crest-derived
mesenchyme are necessary for normal pharyngeal arch development. Disruption of …
mesenchyme are necessary for normal pharyngeal arch development. Disruption of …
Spectrum of heart disease associated with murine and human GATA4 mutation
SK Rajagopal, Q Ma, D Obler, J Shen… - Journal of molecular and …, 2007 - Elsevier
The transcription factor GATA4 is essential for heart morphogenesis. Heterozygous mutation
of GATA4 causes familial septal defects. However, the phenotypic spectrum of heterozygous …
of GATA4 causes familial septal defects. However, the phenotypic spectrum of heterozygous …
Genetics of congenital heart disease
AA Richards, V Garg - Current cardiology reviews, 2010 - ingentaconnect.com
Cardiovascular malformations are the most common type of birth defect and result in
significant mortality worldwide. The etiology for the majority of these anomalies remains …
significant mortality worldwide. The etiology for the majority of these anomalies remains …
[HTML][HTML] Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development
M Maitra, MK Schluterman, HA Nichols… - Developmental …, 2009 - Elsevier
Congenital heart disease is the most common type of birth defect with an incidence of 1%.
Previously, we described a point mutation in GATA4 that segregated with cardiac defects in …
Previously, we described a point mutation in GATA4 that segregated with cardiac defects in …
A molecular pathway revealing a genetic basis for human cardiac and craniofacial defects
H Yamagishi, V Garg, R Matsuoka, T Thomas… - Science, 1999 - science.org
Microdeletions of chromosome 22q11 are the most common genetic defects associated with
cardiac and craniofacial anomalies in humans. A screen for mouse genes dependent on …
cardiac and craniofacial anomalies in humans. A screen for mouse genes dependent on …