Table of contents

Therapeutics

• Review: SSRIs are as effective as tricyclics and have fewer side effects, but their cost-effectiveness has not been established (1 December, 1996)
• Moclobemide was an effective antidepressant in elderly patients with cognitive decline and depression (1 December, 1996)
• Informed consent decreased patient interest in prostate-specific antigen screening (1 December, 1996)
• Zinc lozenges reduced the duration of common cold symptoms (1 December, 1996)
• Intranasal ipratropium bromide reduced rhinorrhea and improved cold symptoms (1 December, 1996)
• Meta-analysis: Addition of chemotherapy to tamoxifen does not extend quality-adjusted survival in postmenopausal breast cancer (1 December, 1996)
• D₂ resection led to higher mortality and morbidity than D₁ resection for gastric cancer

  (1 December, 1996)
• A single dose of ceftriaxone reduced the incidence of wound and nosocomial infections after surgery for closed fractures (1 December, 1996)
• Meta-analysis: Shouldice technique is superior to the Bassini or McVay methods of hernia repair (1 December, 1996)
• Normothermia during colorectal resection reduced surgical-wound infection and length of hospital stay (1 December, 1996)
• Bupivacaine–norepinephrine was effective and safe during laceration repair in children (1 December, 1996)
• Carvedilol reduced mortality and hospitalization in chronic heart failure (1 December, 1996)
• Ardeparin plus graduated compression stockings prevented DVT after knee surgery (1 December, 1996)
• Fish oil reduced relapse and maintained remission in Crohn disease (1 December, 1996)
• Famciclovir reduced lesion healing time in recurrent genital herpes (1 December, 1996)
• Lamivudine plus zidovudine was an effective Initial therapy for HIV-1 infection (1 December, 1996)
• Lamivudine plus zidovudine was more effective than continued zidovudine monotherapy for HIV-1 infection (1 December, 1996)
• Meta-analysis: Antibiotics at the time of a therapeutic abortion protect against upper genital tract infections (1 December, 1996)
• Greater access to primary care increased both patient satisfaction and hospital readsnissions (1 December, 1996)